Browsing by Author "HAUEISEN, Jens"
Now showing 1 - 3 of 3
Results Per Page
Sort Options
Item An Experimental Study on the Effect of the Anisotropic Regions in a Realistically Shaped Torso Phantom(Annals of Biomedical Engineering, 2008-07-04) ŞENGÜL, Gökhan; LIEHR, Mario; HAUEISEN, Jens; BAYSAL, UğurDetermination of electrically active regions in the human body by observing generated bioelectric and/or biomagnetic signals is known as source reconstruction. In the reconstruction process, it is assumed that the volume conductor consists of isotropic compartments and homoge neous tissue bioelectric parameters but this assumption introduces errors when the tissue of interest is anisotropic. The aim of this study was to investigate changes in the measured signal strengths and the estimated positions and orientations of current dipoles in a realistically shaped torso phantom having a heart region built from single guar gum skeins. Electric data were recorded with 60 electrodes on the front of the chest and 195 sensors measured the magnetic field 2 cm above the chest. The artificial rotating dipoles were located underneath the anisotropic skeins distant from the sensors. It was found that the signal strengths and estimated dipole orientations were influenced by the anisotropy while the estimated dipole positions were not significantly influ enced. The signal strength was reduced between 17% and 43% for the different dipole positions when comparing the parallel alignment of dipole orientation and anisotropy direction with the orthogonal alignment. The largest error in the estimation of dipole orientation was 42 degrees. The observed changes in the magnetic fields and electric poten tials can be explained by the fact that the anisotropic skeins force the current along its direction. We conclude that taking into account anisotropic structures in the volume conductor might improve signal analysis as well as source strength and orientation estimations for bioelectric and biomagnetic investigations.Item Effects of anisotropy in a physical torso phantom on source reconstructions from a current dipole(Noninvasive Functional Source Imaging of the Brain and Heart and the International Conference on Functional Biomedical Imaging, 2007-01-03) LIEHR, Mario; ŞENGÜL, Gökhan; BAYSAL, Uğur; HAUEISEN, JensIn this study, we investigated experimentally the influence of anisotropic compartments on source reconstruction using phantom measurements with an artificial current dipole as signal source. The anisotropic compartment was built from single skeins with a nine times higher conductivity than the surrounding solution. We placed the dipole at the lower borders of the anisotropic bulk and measured the magnetic field and the electric potential for each dipole location. The current dipole was rotated in relation to the anisotropic skeins and potentials and fields were recorded for different angles between anisotropic skeins and current dipole. We found that the estimated dipole orientations are strongly influenced by the anisotropy, while the reconstructed position of the dipole is not significantly influenced. We conclude that for bioelectric and biomagnetic source reconstruction, it is necessary to take into account anisotropic structures in the volume conductor if dipole orientations are of interest.Item İnsan Kafasındaki Dokuların Öziletkenliklerinin in vivo E/MEG Verileri ile Kestirilmesi ve Üç Değişik Kestirim Algoritma Sonuçlarının Karşılaştırılması(Signal Processing and Communications Applications Conference, 2004-08-03) ŞENGÜL, Gökhan; BAYSAL, Uğur; HAUEISEN, JensDoku öziletkenliklerinin bilinmesi, insan vücudunun güvenilir hacim iletken modellerinin oluşturulmasında ve ileri/ters biyoelektrik alan problemlerinin çözümünde gereklidir. Bu çalışmada, insan kafasindaki dokulann öziletkenliklerinin EEG ve MEG verileri kullanılarak in vivo kestirimi ipin üç farklı kestirim algoritmasi kullanılarak elde edilen sonuçlar karşılaştırılmıştır. Uygulanan bu algoritmalar; En Küçük Hatalar Karesi (E.K.H.K) kestirim algoritmasi, Bayesian MAP kestirim algoritmasi ve istatistiksel Kısıtlı Minimum Ortalama Hatalar Karesi (1.K.M.O.H.K) algoritmasıdır. Algoritmalar, geometrik yapı, ön bilgisi ile doku öziletkenlikleri ile doğrusallaştırma ve enstrümantasyon gürültüsünün istatistiksel ön bilgilerini girdi olarak kullanır. E/MEG verileri, medyan sinirin uyarıkdığı kaynak konumlandırma deneyinden sırasıyla 32 kanallı EEG ve 31 kanallı magnetometre ile somatosensory korteks üzerinden ölçülmüştür. Kafanın anatomik geometri bilgisi 256 adet TI ağırlıklı MRI görüntüden elde edilmiş ve kafa derisi, kafatası ve beyin olarak homojen üç bölgeye bölütlendirilmiştir. Sözkonusu algoritmalar kullanılarak kafa derisi, kafatası ve beyin öziletkenlikleri ve hata oranları üç farklı algoritma ile kestirilmiştir. Hata oranları E.K.H.K için %90, Bayesian Map kestirim algoriması için % 20.5 ve İ.K.M.O.H.K algoritması için %12.5 olarak hesaplanmıştır. Sonuçta İ.K.M.O.H.K algoritmasının diğer algoritmalara kıyasla daha düşük hata oranları verdiği gösterilmiştir.